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CATH Superfamily 3.90.1200.10

Aminoglycoside phosphotransferase (APH), C-terminal lobe

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7519: Neomycin phosphotransferase III

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Kanamycin kinase. [EC: 2.7.1.95]
ATP + kanamycin = ADP + kanamycin 3'-phosphate.
  • Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A.
  • An enzyme from Pseudomonas aeruginosa also acts on butirosin.
 103 A0A023ZZT8 A0A059N2T2 A0A069FZ75 A0A078RD37 A0A088F9G6 A0A0D0YZX5 A0A0D5C7M3 A0A0E1AK15 A0A0M1XEH9 A0A0M1XV73
(93 more...)