View in Gene3D

CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 81659: Acetylornithine aminotransferase 2

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetylornithine transaminase. [EC: 2.6.1.11]
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
 1551 A0A010T3I8 A0A011AH89 A0A011MNB3 A0A011P141 A0A011Q286 A0A011QP15 A0A011U1D8 A0A014LA05 A0A014Q995 A0A022G4T6
(1541 more...)
Succinylornithine transaminase. [EC: 2.6.1.81]
N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on N(2)-acetyl-L-ornithine and L-ornithine, but more slowly.
  • In Pseudomonas aeruginosa, the arginine-inducible succinylornithine transaminase, EC 2.6.1.11 and EC 2.6.1.13 activities are catalyzed by the same enzyme, but this is not the case in all species.
  • This is the third enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
 9 A0A0C6P787 A0A0H2ZLL5 A0A157WIG5 A0A1C7BCD2 A0A1D5BVS8 A0A1M8IPN9 Q7WDN7 Q9I606 V6A8T3
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]
N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2- L-amino-6-oxoheptanedioate + L-glutamate.
    		 1 R8AN22
    Ornithine aminotransferase. [EC: 2.6.1.13]
    L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
      		 1 Q88QW2
      CATH-Gene3D is a Global Biodata Core Resource Learn more...