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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81621: Threonine aldolase, putative (Eurofung)

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-threonine aldolase. [EC: 4.1.2.5]
L-threonine = glycine + acetaldehyde.
  • This enzyme is specific for L-threonine and can not utilize L-allo- threonine.
  • Different from EC 4.1.2.49 and EC 4.1.2.48.
 4 A3LRY0 B9W957 B9WLT2 K0KHY5
Alanine racemase. [EC: 5.1.1.1]
L-alanine = D-alanine.
    		 2 B8LXV7 Q9UW18
    Low-specificity L-threonine aldolase. [EC: 4.1.2.48]
    (1) L-threonine = glycine + acetaldehyde. (2) L-allo-threonine = glycine + acetaldehyde.
    • The low-specificity L-threonine aldolase can act on both L-threonine and L-allo-threonine.
    • The enzyme from Escherichia coli can also act on L-threo-phenylserine and L-erythro-phenylserine.
    • The enzyme can also catalyze the aldol condensation of glycolaldehyde and glycine to form 4-hydroxy-L-threonine, an intermediate of pyridoxal phosphate biosynthesis.
    • Different from EC 4.1.2.5 and EC 4.1.2.49.
    		 1 O13427
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