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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81476: Purine catabolism protein PucG

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Serine--pyruvate transaminase. [EC: 2.6.1.51]
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
  • The liver enzyme may be identical with EC 2.6.1.44.
 10 A0A075K6Q9 A0A075K6Q9 A0A0K0HYW9 A0A0K0HYW9 A0A150L1E2 A0A150L1E2 A0A1G4LEZ5 A0A1G4LEZ5 Q54GT6 Q54GT6
Alanine--glyoxylate transaminase. [EC: 2.6.1.44]
L-alanine + glyoxylate = pyruvate + glycine.
  • With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate.
  • A second component also catalyzes the reaction of EC 2.6.1.51.
 8 A0A0K0HYW9 A0A0K0HYW9 A0A150L1E2 A0A150L1E2 A0A1G4LEZ5 A0A1G4LEZ5 Q54GT6 Q54GT6
Ureidoglycolate lyase. [EC: 4.3.2.3]
(S)-ureidoglycolate = glyoxylate + urea.
  • This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation.
  • Not to be confused with EC 3.5.1.116 which releases ammonia rather than urea.
 6 A0A0A0TZ07 A0A0A0TZ07 A0A1A5VT59 A0A1A5VT59 E1UPS7 E1UPS7
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