View in Gene3D

CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 81462: Putrescine aminotransferase domain protein

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Putrescine aminotransferase. [EC: 2.6.1.82]
Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O.
  • The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19.
  • Cadaverine and spermidine can also act as substrates.
  • Forms part of the arginine catabolism pathway.
 1296 A0A017IA89 A0A017IA89 A0A023V3M0 A0A023V3M0 A0A023Z3B0 A0A023Z3B0 A0A024KNE0 A0A024KNE0 A0A024L9J0 A0A024L9J0
(1286 more...)
Ornithine aminotransferase. [EC: 2.6.1.13]
L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
    		 6 A0A0H7YUY2 A0A0H7YUY2 A0A0K3R0U0 A0A0K3R0U0 E2X7K5 E2X7K5
    Diamine transaminase. [EC: 2.6.1.29]
    An alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.
      		 4 A0A090NI87 A0A090NI87 A0A0A6ZYZ6 A0A0A6ZYZ6
      2,4-dienoyl-CoA reductase (NADPH). [EC: 1.3.1.34]
      Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5- tetradehydroacyl-CoA + NADPH.
      • Best substrates for reduction contain a 2,4-diene structure with chain length C(8) or C(10).
      		 2 K8CIL2 K8CIL2