The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81249: Dopa decarboxylase isoform 1

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aromatic-L-amino-acid decarboxylase. [EC: 4.1.1.28]
(1) L-dopa = dopamine + CO(2). (2) 5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO(2).
  • Also acts on other aromatic L-amino acids, including L-tryptophan.
  • Formerly EC 4.1.1.26 and EC 4.1.1.27.
114 A0A061ILT2 A0A061ILT2 A0A0B2PP13 A0A0B2PP13 A0A0G3VHZ3 A0A0G3VHZ3 A0A0S2Z3N4 A0A0S2Z3N4 A1Z6N2 A1Z6N2
(104 more...)
Tyrosine decarboxylase. [EC: 4.1.1.25]
L-tyrosine = tyramine + CO(2).
  • The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.
62 A0A0B2PP13 A0A0B2PP13 A0A0B2Q3G6 A0A0B2Q3G6 A0A0B2QNE1 A0A0B2QNE1 A0A0B2R021 A0A0B2R021 A0A0G3VFZ2 A0A0G3VFZ2
(52 more...)
Histidine decarboxylase. [EC: 4.1.1.22]
L-histidine = histamine + CO(2).
    16 A0A0B4KEQ1 A0A0B4KEQ1 A0A0G3VI98 A0A0G3VI98 I0B8M2 I0B8M2 P16453 P16453 P19113 P19113
    (6 more...)
    Transferred entry: 4.1.1.28. [EC: 4.1.1.26]
      4 O61717 O61717 O61718 O61718