The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81207: 5-aminovalerate aminotransferase DavT

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-aminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.19]
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
  • Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
12 A0A0M0KUQ1 A0A0T8PUI1 A0A164U3S8 A0A1B2B264 A0A1G4LG21 A7Z1D8 E0U300 G4F002 G4NQZ8 L8ACT4
(2 more...)
(S)-3-amino-2-methylpropionate transaminase. [EC: 2.6.1.22]
(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3- oxopropanoate + L-glutamate.
  • Also acts on beta-alanine and other omega-amino acids having carbon chains between 2 and 5.
  • The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.
5 A0A164U3S8 A0A1B2B264 G4F002 L8ACT4 P94427
5-aminovalerate transaminase. [EC: 2.6.1.48]
5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
    4 A0A0K6JKW0 A0A0K6K4T2 A0A0K6KQI6 A0A0K6L2A8
    Acetylornithine transaminase. [EC: 2.6.1.11]
    N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
    • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
    1 A0A0T8PUI1
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