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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 81005: Siderophore biosynthesis diaminobutyrate-2-oxoglut...

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.
  • Differs from EC 2.6.1.46, which has pyruvate as the amino-group acceptor.
  • This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
 496 A0A009ETH4 A0A009GAI7 A0A009HGK0 A0A009I3D2 A0A009INR5 A0A009KB47 A0A009KLP3 A0A009KRA0 A0A009N3J8 A0A009Q3A5
(486 more...)
Diaminobutyrate decarboxylase. [EC: 4.1.1.86]
L-2,4-diaminobutanoate = propane-1,3-diamine + CO(2).
  • N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates.
  • In Acinetobacter baumannii it is cotranscribed with the neighboring dat gene that encodes EC 2.6.1.76, which can supply the substrate for the decarboxylase.
 4 A0A090S3R2 A0A090SDM9 A0A090T3R2 A0A0B8QAM7
Acetylornithine transaminase. [EC: 2.6.1.11]
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
 3 A0A0X9J8C8 A0A0Y0BI95 E1X6A3
4-aminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.19]
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
  • Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
 2 E0SIE8 U1BCM3
Diaminobutyrate--pyruvate transaminase. [EC: 2.6.1.46]
L-2,4-diaminobutanoate + pyruvate = L-aspartate 4-semialdehyde + L-alanine.
    		 1 E5AU63
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