The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 80480: Histidinol-phosphate aminotransferase 1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histidinol-phosphate transaminase. [EC: 2.6.1.9]
L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
    2032 A0A011M174 A0A011M174 A0A014N756 A0A014N756 A0A017IEG6 A0A017IEG6 A0A022PES3 A0A022PES3 A0A023VD69 A0A023VD69
    (2022 more...)
    Histidinol dehydrogenase. [EC: 1.1.1.23]
    L-histidinol + H(2)O + 2 NAD(+) = L-histidine + 2 NADH.
    • Also oxidizes L-histidinal.
    • The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31.
    4 A0A022PES3 A0A022PES3 Q7N6I1 Q7N6I1
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