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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 80178: Acetylornithine and succinylornithine aminotransfe...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinylornithine transaminase. [EC: 2.6.1.81]
N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on N(2)-acetyl-L-ornithine and L-ornithine, but more slowly.
  • In Pseudomonas aeruginosa, the arginine-inducible succinylornithine transaminase, EC 2.6.1.11 and EC 2.6.1.13 activities are catalyzed by the same enzyme, but this is not the case in all species.
  • This is the third enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.81, EC 1.2.1.71 and EC 3.5.1.96.
 816 A0A017IFL2 A0A017IFL2 A0A023VCR3 A0A023VCR3 A0A023YY10 A0A023YY10 A0A024KVJ3 A0A024KVJ3 A0A025CQF7 A0A025CQF7
(806 more...)
Acetylornithine transaminase. [EC: 2.6.1.11]
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
  • Also acts on L-ornithine and N(2)-succinyl-L-ornithine.
 384 A0A014PT64 A0A014PT64 A0A059IF35 A0A059IF35 A0A060UZU6 A0A060UZU6 A0A060VH71 A0A060VH71 A0A063XY54 A0A063XY54
(374 more...)
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]
N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2- L-amino-6-oxoheptanedioate + L-glutamate.
    		 382 A0A014PT64 A0A014PT64 A0A059IF35 A0A059IF35 A0A060UZU6 A0A060UZU6 A0A060VH71 A0A060VH71 A0A063XY54 A0A063XY54
    (372 more...)
    Aspartate transaminase. [EC: 2.6.1.1]
    L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
    • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
    • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
    		 2 C8T6H8 C8T6H8