View in Gene3D

CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 63296: Low specificity L-threonine aldolase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-threonine aldolase. [EC: 4.1.2.5]
L-threonine = glycine + acetaldehyde.
  • This enzyme is specific for L-threonine and can not utilize L-allo- threonine.
  • Different from EC 4.1.2.49 and EC 4.1.2.48.
 380 A0A017IK21 A0A017IK21 A0A023YUC1 A0A023YUC1 A0A024KQT2 A0A024KQT2 A0A025C7X4 A0A025C7X4 A0A026UII5 A0A026UII5
(370 more...)
Low-specificity L-threonine aldolase. [EC: 4.1.2.48]
(1) L-threonine = glycine + acetaldehyde. (2) L-allo-threonine = glycine + acetaldehyde.
  • The low-specificity L-threonine aldolase can act on both L-threonine and L-allo-threonine.
  • The enzyme from Escherichia coli can also act on L-threo-phenylserine and L-erythro-phenylserine.
  • The enzyme can also catalyze the aldol condensation of glycolaldehyde and glycine to form 4-hydroxy-L-threonine, an intermediate of pyridoxal phosphate biosynthesis.
  • Different from EC 4.1.2.5 and EC 4.1.2.49.
 194 A0A024KQT2 A0A024KQT2 A0A026UII5 A0A026UII5 A0A027U7B3 A0A027U7B3 A0A028AK30 A0A028AK30 A0A028E477 A0A028E477
(184 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...