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CATH Superfamily 3.90.1150.10

Aspartate Aminotransferase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41939: Aminotransferase YbdL

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methionine transaminase. [EC: 2.6.1.88]
L-methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an L-amino acid.
  • The enzyme is most active with L-methionine.
  • It participates in the L-methionine salvage pathway from S-methyl- 5'-thioadenosine, a by-product of polyamine biosynthesis.
  • The enzyme from the bacterium Klebsiella pneumoniae can use several different amino acids as amino donor, with aromatic amino acids being the most effective.
  • The enzyme from the plant Arabidopsis thaliana is also a part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates.
 83 A0A027TEJ8 A0A028A2Y9 A0A028DLM0 A0A029L0W4 A0A061KPU4 A0A070DEX9 A0A070SRM4 A0A070UQS4 A0A073FZC9 A0A073GK84
(73 more...)
Aspartate transaminase. [EC: 2.6.1.1]
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
  • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
  • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
 28 A0A029L0W4 A0A070SRM4 A0A0A0FAQ9 A0A0E1LUL8 A0A0M7P046 A0A125X7A2 A0A142UVC4 A0A1J0H8R8 D8AUD1 D8BA72
(18 more...)