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CATH Superfamily 3.90.110.10

Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2209: L-lactate dehydrogenase A chain

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-lactate dehydrogenase. [EC: 1.1.1.27]
(S)-lactate + NAD(+) = pyruvate + NADH.
  • Also oxidizes other (S)-2-hydroxymonocarboxylic acids.
  • NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.
 748 A0A016RWW2 A0A016RX04 A0A016RX43 A0A016RXR0 A0A016U5S8 A0A016U625 A0A016U6S0 A0A016WRF8 A0A023ENR9 A0A024CCI1
(738 more...)