The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44355: TLR4 interactor with leucine rich repeats

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
1 Q7L0X0 (/IDA)
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
1 Q9DBY4 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cytokine production involved in immune response GO:0002718
Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
1 Q7L0X0 (/IDA)
Regulation of cytokine production involved in immune response GO:0002718
Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
1 Q9DBY4 (/ISO)
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
1 Q7L0X0 (/IDA)
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
1 Q9DBY4 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipopolysaccharide receptor complex GO:0046696
A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.
1 Q7L0X0 (/IDA)
Lipopolysaccharide receptor complex GO:0046696
A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.
1 Q9DBY4 (/ISO)