The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 106442: Volume-regulated anion channel subunit LRRC8C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
5 A5PK13 (/ISS) Q3KRC6 (/ISS) Q66JT1 (/ISS) Q68F79 (/ISS) Q8R502 (/ISS)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
2 Q6NSJ5 (/IMP) Q8TDW0 (/IMP)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
2 Q66JT1 (/ISO) Q8R502 (/ISO)
Volume-sensitive anion channel activity GO:0005225
Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
2 Q6NSJ5 (/TAS) Q8TDW0 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q6NSJ5 (/IPI) Q8TDW0 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anion transmembrane transport GO:0098656
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
5 A5PK13 (/ISS) Q3KRC6 (/ISS) Q66JT1 (/ISS) Q68F79 (/ISS) Q8R502 (/ISS)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
2 Q6NSJ5 (/TAS) Q8TDW0 (/TAS)
Anion transmembrane transport GO:0098656
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2 Q6NSJ5 (/IMP) Q8TDW0 (/IMP)
Anion transmembrane transport GO:0098656
A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2 Q66JT1 (/ISO) Q8R502 (/ISO)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 Q8R502 (/IDA)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 Q8R502 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 A5PK13 (/ISS) Q3KRC6 (/ISS) Q66JT1 (/ISS) Q68F79 (/ISS) Q8R502 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 A5PK13 (/ISS) Q3KRC6 (/ISS) Q66JT1 (/ISS) Q68F79 (/ISS) Q8R502 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A5PK13 (/ISS) Q3KRC6 (/ISS) Q66JT1 (/ISS) Q68F79 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q6NSJ5 (/IDA) Q8TDW0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q66JT1 (/ISO) Q8R502 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q6NSJ5 (/IDA) Q8TDW0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q66JT1 (/ISO) Q8R502 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q6NSJ5 (/TAS) Q8TDW0 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q6NSJ5 (/IMP) Q8TDW0 (/IMP)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q66JT1 (/ISO) Q8R502 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q8R502 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8TDW0 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8R502 (/ISO)