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CATH Superfamily 3.80.10.10

Ribonuclease Inhibitor

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 105744: U2 small nuclear ribonucleoprotein A

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Propanediol-phosphate dehydrogenase. [EC: 1.1.1.7]
Propane-1,2-diol 1-phosphate + NAD(+) = hydroxyacetone phosphate + NADH.
    		 3 A0A0F4Z448 A2R2Y2 G3XP60
    Initiation-specific alpha-1,6-mannosyltransferase. [EC: 2.4.1.232]
    Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
    • In Saccharomyces cerevisiae, this enzyme catalyzes an essential step in the outer chain elongation of N-linked oligosaccharides.
    • Man(8)GlcNAc and Man(9)GlcNAc are equally good substrates.
    		 1 A0A0L1HL99
    GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase. [EC: 2.4.1.132]
    GDP-D-mannose + D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc- diphosphodolichol = GDP + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc- beta-(1->4)-GlcNAc-diphosphodolichol.
    • The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway.
    • Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an alpha-1,3-mannosylation of D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D- GlcNAc-diphosphodolichol, followed by an alpha-1,6-mannosylation (cf. EC 2.4.1.257), to form the first branched pentasaccharide intermediate of the dolichol pathway.
    		 1 A0A0L1HL99
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