The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 105500: Leucine-rich repeat transmembrane protein FLRT1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signal transducer activity, downstream of receptor GO:0005057
Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.
|
2 | O43155 (/NAS) Q9NZU1 (/NAS) |
|
Fibroblast growth factor receptor binding GO:0005104
Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR).
|
2 | Q6RKD8 (/IPI) Q8BLU0 (/IPI) |
|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
2 | O43155 (/NAS) Q9NZU1 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8BLU0 (/IPI) |
|
Chemorepellent activity GO:0045499
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
|
1 | Q8BLU0 (/IDA) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
3 | D3ZTV3 (/ISS) O43155 (/ISS) Q9NZU1 (/ISS) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
|
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
2 | Q6RKD8 (/IMP) Q8BLU0 (/IMP) |
|
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
|
2 | O43155 (/TAS) Q9NZU1 (/TAS) |
|
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
2 | Q6RKD8 (/IDA) Q8BLU0 (/IDA) |
|
Cell adhesion involved in heart morphogenesis GO:0061343
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
|
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
2 | D3ZTV3 (/ISS) O43155 (/ISS) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q8BLU0 (/IMP) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q8BLU0 (/IGI) |
|
Dendrite development GO:0016358
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell.
|
1 | Q6RKD8 (/IMP) |
|
Dendrite development GO:0016358
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell.
|
1 | Q9NZU1 (/ISS) |
|
Cell adhesion involved in heart morphogenesis GO:0061343
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
|
1 | Q8BLU0 (/IMP) |
|
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
1 | Q8BLU0 (/IMP) |
|
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q6RKD8 (/IMP) |
|
Neuron projection extension GO:1990138
Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
1 | Q9NZU1 (/ISS) |
|
Regulation of neuron migration GO:2001222
Any process that modulates the frequency, rate or extent of neuron migration.
|
1 | Q8BLU0 (/IGI) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | D3ZTV3 (/ISS) O43155 (/ISS) Q9NZU1 (/ISS) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
3 | D3ZTV3 (/ISS) O43155 (/ISS) Q9NZU1 (/ISS) |
|
Proteinaceous extracellular matrix GO:0005578
A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
|
2 | O43155 (/NAS) Q9NZU1 (/NAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | Q6RKD8 (/IDA) Q8BLU0 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O43155 (/TAS) Q9NZU1 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q6RKD8 (/IDA) Q8BLU0 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O43155 (/NAS) Q9NZU1 (/NAS) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
2 | Q6RKD8 (/IDA) Q8BLU0 (/IDA) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | O43155 (/IDA) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | Q8BLU0 (/ISO) |
|
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q6RKD8 (/IDA) |
|
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q9NZU1 (/ISS) |
|
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
|
1 | Q6RKD8 (/IDA) |
|
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
|
1 | Q9NZU1 (/ISS) |
|
Neuron projection terminus GO:0044306
The specialized, terminal region of a neuron projection such as an axon or a dendrite.
|
1 | Q6RKD8 (/IDA) |
|
Neuron projection terminus GO:0044306
The specialized, terminal region of a neuron projection such as an axon or a dendrite.
|
1 | Q9NZU1 (/ISS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q6RKD8 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9NZU1 (/ISS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | O43155 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q8BLU0 (/ISO) |
