The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
PPM-type phosphatase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11501: Phosphatase 2C family protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q501F9 (/IPI) Q84T94 (/IPI) Q9LHJ9 (/IPI)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
2 Q12511 (/IDA) Q8RWN7 (/IDA)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2 O82302 (/IDA) Q8RWN7 (/IDA)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 Q12511 (/ISS)
[pyruvate dehydrogenase (lipoamide)] phosphatase activity GO:0004741
Catalysis of the reaction:
1 O14189 (/ISO)
[pyruvate dehydrogenase (lipoamide)] phosphatase activity GO:0004741
Catalysis of the reaction:
1 Q12511 (/ISS)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
1 Q501F9 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 O82302 (/IGI) Q8RWN7 (/IGI)
Maintenance of meristem identity GO:0010074
The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
2 O82302 (/IGI) Q8RWN7 (/IGI)
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
2 Q9LQN6 (/IMP) Q9ZV25 (/IMP)
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
1 O14189 (/NAS)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 Q12511 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 G4NAS8 (/IMP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 O82302 (/IGI)
Meristem structural organization GO:0009933
Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
1 O82302 (/IGI)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 G4NAS8 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q5A388 (/IMP)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
1 Q12511 (/IMP)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
1 Q12511 (/IMP)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q5A388 (/IMP)
Negative regulation of leaf senescence GO:1900056
Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.
1 Q501F9 (/IMP)
Negative regulation of defense response to bacterium GO:1900425
Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.
1 Q9LHJ9 (/IDA)
Regulation of spore germination GO:1904359
Any process that modulates the frequency, rate or extent of spore germination.
1 Q5B158 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 O82302 (/IDA) Q8RWN7 (/IDA) Q9LHJ9 (/IDA) Q9LQN6 (/IDA) Q9SD12 (/IDA) Q9ZV25 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 O14189 (/IDA) Q12511 (/IDA) Q5A388 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q501F9 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O14189 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q12511 (/IDA)