View in Gene3D

CATH Superfamily 3.60.15.10

Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 29266: UPF0173 metal-dependent hydrolase RL2074

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D. [EC: 3.1.4.54]
An N-acylphosphatidylethanolamine + H(2)O = an N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate.
  • This enzyme is involved in the biosynthesis of anandamide.
  • It does not hydrolyze phosphatidylcholine and phosphatidylethanolamine.
  • No transphosphatidation.
 20 A0A0L8VFP5 A0A0L8VFP5 A0A1A0D280 A0A1A0D280 A0A1A5VEJ9 A0A1A5VEJ9 B3LKX0 B3LKX0 B5VT60 B5VT60
(10 more...)
Hydroxyacylglutathione hydrolase. [EC: 3.1.2.6]
S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy carboxylate.
  • Also hydrolyzes S-acetoacetylglutathione, more slowly.
  • Formerly EC 3.1.2.8.
 4 A0A0A2H8G3 A0A0A2H8G3 A0A1A7KJV0 A0A1A7KJV0