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CATH Superfamily 3.60.15.10

Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 29234: Putative beta-lactamase family protein

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydroxyacylglutathione hydrolase. [EC: 3.1.2.6]
S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy carboxylate.
  • Also hydrolyzes S-acetoacetylglutathione, more slowly.
  • Formerly EC 3.1.2.8.
 285 A0A029KYM4 A0A045GUP2 A0A066SNM9 A0A069XR11 A0A070T3X9 A0A073KKP9 A0A081HUI5 A0A083ZT12 A0A085R6Y9 A0A090NPD5
(275 more...)
Beta-lactamase. [EC: 3.5.2.6]
A beta-lactam + H(2)O = a substituted beta-amino acid.
  • Zinc is only requires in class-B enzymes.
  • A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins.
  • Formerly EC 3.5.2.8.
 12 A0A0E1X3H2 A0A0H3AQK1 C0G7E1 C7LDB0 C9VBU4 D0P8X9 D0RJ13 D6LPI9 D7GZN1 E2PRZ3
(2 more...)
Aryldialkylphosphatase. [EC: 3.1.8.1]
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.
  • Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids.
  • Inhibited by chelating agents.
  • Previously regarded as identical with EC 3.1.1.2.
 1 A0A141FAA1
IMP dehydrogenase. [EC: 1.1.1.205]
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.
  • The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.
  • Formerly EC 1.2.1.14.
 1 U2WU08
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