The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".
FunFam 29171: Ribonuclease Z 2, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3'-tRNA processing endoribonuclease activity GO:0042781
Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
|
5 | F4J1H7 (/IDA) P36159 (/IDA) P87168 (/IDA) Q10155 (/IDA) Q8VYS2 (/IDA) |
|
3'-tRNA processing endoribonuclease activity GO:0042781
Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
|
2 | P87168 (/IMP) Q10155 (/IMP) |
|
Endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891
Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
|
1 | Q8MKW7 (/IMP) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
TRNA 3'-end processing GO:0042780
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
|
3 | F4J1H7 (/IDA) P36159 (/IDA) Q8VYS2 (/IDA) |
|
Polycistronic mRNA processing GO:0031426
The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.
|
2 | P87168 (/IMP) Q8MKW7 (/IMP) |
|
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
|
1 | Q8MKW7 (/IMP) |
|
TRNA splicing, via endonucleolytic cleavage and ligation GO:0006388
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
|
1 | Q8MKW7 (/IMP) |
|
TRNA export from nucleus GO:0006409
The directed movement of tRNA from the nucleus to the cytoplasm.
|
1 | Q8MKW7 (/IMP) |
|
Ventral cord development GO:0007419
The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
|
1 | Q8MKW7 (/IMP) |
|
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
|
1 | Q8MKW7 (/IMP) |
|
TRNA 3'-trailer cleavage, endonucleolytic GO:0034414
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
|
1 | P36159 (/IDA) |
|
TRNA 3'-trailer cleavage, endonucleolytic GO:0034414
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
|
1 | P36159 (/IMP) |
|
Germ cell proliferation GO:0036093
The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
|
1 | Q8MKW7 (/IMP) |
|
TRNA 3'-trailer cleavage GO:0042779
Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both.
|
1 | Q10155 (/IMP) |
|
TRNA 3'-end processing GO:0042780
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
|
1 | Q8MKW7 (/IMP) |
|
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
1 | Q8MKW7 (/IMP) |
|
Lateral inhibition GO:0046331
Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
|
1 | Q8MKW7 (/IMP) |
|
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
1 | Q8MKW7 (/IMP) |
|
Mitochondrial tRNA 3'-trailer cleavage, endonucleolytic GO:0072684
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.
|
1 | P87168 (/IDA) |
|
Mitochondrial tRNA 3'-trailer cleavage, endonucleolytic GO:0072684
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.
|
1 | P87168 (/IMP) |
|
Nuclear tRNA 3'-trailer cleavage, endonucleolytic GO:1902375
Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus.
|
1 | Q10155 (/IMP) |
|
Mitochondrial tRNA 3'-end processing GO:1990180
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
|
1 | P36159 (/IDA) |
|
Mitochondrial tRNA 3'-end processing GO:1990180
The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
|
1 | P36159 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P36159 (/IDA) Q10155 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P36159 (/IDA) P87168 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8MKW7 (/NAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q8MKW7 (/NAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P87168 (/IDA) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | P87168 (/IDA) |
