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CATH Superfamily 3.60.110.10

Carbon-nitrogen hydrolase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Carbon-nitrogen hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3462: Amidohydrolase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(R)-amidase. [EC: 3.5.1.100]
(1) (R)-piperazine-2-carboxamide + H(2)O = (R)-piperazine-2-carboxylate + NH(3). (2) Beta-alaninamide + H(2)O = beta-alanine + NH(3).
  • In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)- piperidine-3-carboxylic acid and NH(3), and (R)-N-tert- butylpiperazine-2-carboxamide is hydrolyzed to (R)-piperazine-2- carboxylic acid and tert-butylamine with lower activity.
  • The enzyme does not act on the other amide substrates which are hydrolyzed by EC 3.5.1.4 (amidase).
 28 A0A045IP04 A0A0H3LCE7 A0A0K2HS44 A0A0T9BJF1 A0A109SKL2 A0A120IZN6 A0A1A9T7P4 A0A1K2L566 A0A1K3TRT6 A0A1K3WX65
(18 more...)