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CATH Superfamily 3.60.10.10

Endonuclease/exonuclease/phosphatase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Endonuclease/exonuclease/phosphatase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6426: Exodeoxyribonuclease III

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Exodeoxyribonuclease III. [EC: 3.1.11.2]
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
  • Preference for double-stranded DNA.
  • Has endonucleolytic activity near apurinic sites on DNA.
  • Similar enzyme: Haemophilus influenzae exonuclease.
  • Formerly EC 3.1.4.27.
 14 A0A0E1B213 A0A0H2ZI82 A0A0H3QLS7 A0A0P1DIL9 A0A157Z099 A0A1C7BK73 A0A1D5BSH5 A0A1E9C0Z8 A0A1F0I111 A0A1G5LW99
(4 more...)