The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Endonuclease/exonuclease/phosphatase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13371: Exodeoxyribonuclease III Xth

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Exodeoxyribonuclease III. [EC: 3.1.11.2]
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
  • Preference for double-stranded DNA.
  • Has endonucleolytic activity near apurinic sites on DNA.
  • Similar enzyme: Haemophilus influenzae exonuclease.
  • Formerly EC 3.1.4.27.
1211 A0A010Q3V9 A0A011NFA3 A0A017IG10 A0A022PFK4 A0A023CAY8 A0A023PYS8 A0A023WSL9 A0A023YXW4 A0A024HIY7 A0A024KW76
(1201 more...)