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CATH Superfamily 3.50.40.10

Phenylalanyl-trna Synthetase, Chain B, domain 3

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phenylalanyl-trna Synthetase, Chain B, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2854: Phenylalanine--tRNA ligase beta subunit

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenylalanine--tRNA ligase. [EC: 6.1.1.20]
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).
    		 756 A0A023HAI3 A0A023HCF6 A0A024V4G7 A0A024W590 A0A031LK49 A0A059I2C1 A0A059I3T0 A0A059TRW4 A0A059Y375 A0A060HFR5
    (746 more...)
    Protein-serine/threonine phosphatase. [EC: 3.1.3.16]
    [a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
    • A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48).
    • The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
    		 1 B7QHR9
    TRNA(Ile)-lysidine synthetase. [EC: 6.3.4.19]
    (tRNA(Ile2))-cytidine(34) + L-lysine + ATP = (tRNA(Ile2))-lysidine(34) + AMP + diphosphate + H(2)O.
    • The bacterial enzyme modifies the wobble base of the CAU anticodon of tRNA(Ile) at the oxo group in position 2 of cytidine(34).
    • This modification determines both codon and amino acid specificities of tRNA(Ile).
    		 1 M5DXI4