The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Mannitol-specific EII; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4542: Sodium bicarbonate cotransporter 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 29 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anion:anion antiporter activity GO:0015301
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
15 B0S7B8 (/IDA) F1QGN4 (/IDA) G5EC65 (/IDA) G5EDF4 (/IDA) M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) P02730 (/IDA)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 O88343 (/IPI) P02730 (/IPI) P04919 (/IPI) Q80ZA5 (/IPI) Q9GL77 (/IPI) Q9Y6R1 (/IPI)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
6 P02730 (/ISS) P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Anion:anion antiporter activity GO:0015301
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
6 P04919 (/ISS) P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Inorganic anion exchanger activity GO:0005452
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).
5 P02730 (/TAS) P04920 (/TAS) P48751 (/TAS) Q2Y0W8 (/TAS) Q6RI88 (/TAS)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
5 O88343 (/ISS) Q4U116 (/ISS) Q9GL77 (/ISS) Q9JI66 (/ISS) Q9XSZ4 (/ISS)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
4 Q9BY07 (/TAS) Q9JI66 (/TAS) Q9Y6M7 (/TAS) Q9Y6R1 (/TAS)
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
4 G5EC65 (/IDA) G5EDF4 (/IDA) P04919 (/IDA) P13808 (/IDA)
Inorganic anion exchanger activity GO:0005452
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).
3 P04919 (/ISS) P15575 (/ISS) P23562 (/ISS)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
3 P04919 (/ISS) P15575 (/ISS) P23562 (/ISS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 P23347 (/IPI) P23348 (/IPI) P23562 (/IPI)
Anion transmembrane transporter activity GO:0008509
Enables the transfer of a negatively charged ion from one side of a membrane to the other.
2 P02730 (/TAS) P04920 (/TAS)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
2 F1QHT2 (/IDA) Q3ZMH2 (/IDA)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
2 Q9BY07 (/NAS) Q9Y6M7 (/NAS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 P23562 (/IPI)
Inorganic anion exchanger activity GO:0005452
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).
1 P02730 (/IDA)
Inorganic anion exchanger activity GO:0005452
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).
1 P04919 (/ISO)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P23562 (/IPI)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
1 Q9Y6R1 (/IMP)
Sodium:bicarbonate symporter activity GO:0008510
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
1 O88343 (/ISO)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 P02730 (/IDA)
Bicarbonate transmembrane transporter activity GO:0015106
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
1 P04919 (/ISO)
Anion:anion antiporter activity GO:0015301
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
1 P04919 (/ISO)
Anion:anion antiporter activity GO:0015301
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
1 P02730 (/TAS)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
1 P02730 (/IPI)
Ankyrin binding GO:0030506
Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
1 P04919 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P02730 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P04919 (/ISO)
Protein anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
1 P02730 (/TAS)

There are 54 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
11 B0S7B8 (/IDA) F1QGN4 (/IDA) M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) P02730 (/IDA) Q8IPI3 (/IDA) Q9VM31 (/IDA)
(1 more)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10 M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) O88343 (/IDA) Q8IPI3 (/IDA) Q9VM31 (/IDA) Q9VM32 (/IDA) Q9Y6R1 (/IDA)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10 M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) P04919 (/IDA) P13808 (/IDA) Q8IPI3 (/IDA) Q9VM31 (/IDA) Q9VM32 (/IDA)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) P02730 (/IDA) Q8IPI3 (/IDA) Q9VM31 (/IDA) Q9VM32 (/IDA)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 P02730 (/TAS) P04920 (/TAS) P23562 (/TAS) P48751 (/TAS) Q2Y0W8 (/TAS) Q9BY07 (/TAS) Q9Y6M7 (/TAS) Q9Y6R1 (/TAS)
Proton transport GO:0015992
The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) Q8IPI3 (/IDA) Q9VM31 (/IDA) Q9VM32 (/IDA)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 P02730 (/ISS) P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q4U116 (/ISS) Q9GL77 (/ISS) Q9JI66 (/ISS) Q9XSZ4 (/ISS)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 O88343 (/ISS) P04919 (/ISS) P15575 (/ISS) P23562 (/ISS)
Epithelial cell development GO:0002064
The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Renal system process GO:0003014
A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Regulation of systemic arterial blood pressure GO:0003073
The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 P02730 (/TAS) P04920 (/TAS) Q6RI88 (/TAS)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
3 O88343 (/TAS) Q6RI88 (/TAS) Q9JI66 (/TAS)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Cerebrospinal fluid secretion GO:0033326
The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Mitochondrion distribution GO:0048311
Any process that establishes the spatial arrangement of mitochondria between and within cells.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
3 D3YVG0 (/IMP) D3YX36 (/IMP) E9Q3M5 (/IMP)
Transport GO:0006810
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
2 P48751 (/TAS) Q9Y6R1 (/TAS)
Synaptic transmission, cholinergic GO:0007271
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse using the neurotransmitter acetylcholine.
2 G5EC65 (/IMP) G5EDF4 (/IMP)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9BY07 (/NAS) Q9Y6M7 (/NAS)
Regulation of synaptic transmission, GABAergic GO:0032228
Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
2 G5EC65 (/IGI) G5EDF4 (/IGI)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
2 G5EC65 (/IMP) G5EDF4 (/IMP)
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
1 Q5DTL9 (/ISO)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O88343 (/ISO)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P04919 (/ISO)
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P23562 (/TAS)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
1 P02730 (/TAS)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
1 Q5DTL9 (/IDA)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P23347 (/IEP)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 P23562 (/IEP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
1 P23562 (/IEP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 Q5DTL9 (/IMP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
1 Q5DTL9 (/IMP)
Response to carbon dioxide GO:0010037
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
1 P23562 (/IDA)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
1 P23562 (/IDA)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O88343 (/IGI)
Bicarbonate transport GO:0015701
The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P04919 (/ISO)
Pyramidal neuron development GO:0021860
The progression of a pyramidal neuron from its initial formation to its mature state.
1 Q5DTL9 (/IMP)
Regulation of cellular pH GO:0030641
Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.
1 Q5DTL9 (/IMP)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 P23562 (/IEP)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q5DTL9 (/IMP)
Locomotory exploration behavior GO:0035641
The specific movement from place to place of an organism in response to a novel environment.
1 Q5DTL9 (/IMP)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
1 P23562 (/IDA)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 P23562 (/IDA)
Response to arsenic-containing substance GO:0046685
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
1 P23562 (/IDA)
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
1 P23347 (/IEP)
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q5DTL9 (/IMP)
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P23562 (/IDA)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 P16283 (/IDA)
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
1 P23347 (/IMP)
Hydrogen ion transmembrane transport GO:1902600
The directed movement of hydrogen ion (proton) across a membrane.
1 Q5DTL9 (/IMP)

There are 40 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 M9PB59 (/IDA) M9PB60 (/IDA) M9PC92 (/IDA) M9PCT2 (/IDA) M9PF01 (/IDA) P16283 (/IDA) P23562 (/IDA) Q5DTL9 (/IDA) Q8IPI3 (/IDA) Q8JZR6 (/IDA)
(3 more)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
9 B0S7B8 (/IDA) P02730 (/IDA) P04919 (/IDA) P13808 (/IDA) P23347 (/IDA) P23562 (/IDA) Q5DTL9 (/IDA) Q9R1N3 (/IDA) Q9Y6R1 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
9 O88343 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q4U116 (/ISS) Q5RBP3 (/ISS) Q9GL77 (/ISS) Q9JI66 (/ISS) Q9TUQ0 (/ISS) Q9XSZ4 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 M9PB59 (/ISS) M9PB60 (/ISS) M9PC92 (/ISS) M9PCT2 (/ISS) M9PF01 (/ISS) Q8IPI3 (/ISS) Q9VM31 (/ISS) Q9VM32 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P02730 (/TAS) P04920 (/TAS) P48751 (/TAS) Q2Y0W8 (/TAS) Q9BY07 (/TAS) Q9Y6M7 (/TAS) Q9Y6R1 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
7 P04919 (/ISS) P15575 (/ISS) P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
6 P02730 (/ISS) P04919 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 O88343 (/TAS) P02730 (/TAS) P48751 (/TAS) Q9JI66 (/TAS) Q9Y6R1 (/TAS)
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
5 P23562 (/ISS) Q2Z1P8 (/ISS) Q2Z1P9 (/ISS) Q5RBP3 (/ISS) Q9TUQ0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 P04919 (/IDA) P04920 (/IDA) P13808 (/IDA) Q8JZR6 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P02730 (/NAS) Q9BY07 (/NAS) Q9Y6M7 (/NAS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
3 O88343 (/ISO) P04919 (/ISO) P13808 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
3 B0S7B8 (/IDA) P23347 (/IDA) Q9R1N3 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 G5EC65 (/IC) G5EDF4 (/IC)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P04920 (/TAS) P48751 (/TAS)
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
2 P02730 (/IDA) P04919 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P02730 (/IDA) Q9Y6R1 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 O88343 (/ISO) P04919 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P02730 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q5DTL9 (/ISA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P04919 (/ISO)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P04920 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 P13808 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P23562 (/IDA)
Intercalated disc GO:0014704
A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
1 P23562 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P13808 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6RI88 (/TAS)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 P23562 (/IDA)
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
1 P04919 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q9R1N3 (/IDA)
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
1 Q9R1N3 (/IDA)
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
1 Q8JZR6 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q8JZR6 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q5DTL9 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q9R1N3 (/IDA)
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
1 P02730 (/IDA)
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
1 P04919 (/ISO)
Apical dendrite GO:0097440
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
1 Q5DTL9 (/IDA)
Basilar dendrite GO:0097441
A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.
1 Q5DTL9 (/IDA)
CA3 pyramidal cell dendrite GO:0097442
A dendrite of a hippocampal CA3 pyramidal cell.
1 Q5DTL9 (/IDA)
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