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CATH Superfamily 3.40.930.10

Mannitol-specific EII; Chain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Mannitol-specific EII; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1116: Phosphoenolpyruvate-protein phosphotransferase of ...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoenolpyruvate--protein phosphotransferase. [EC: 2.7.3.9]
Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)- phospho-L-histidine.
  • Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.
  • A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme.
 116 A0A023Z0E8 A0A024KY38 A0A024KZF9 A0A025CVI1 A0A027TZ44 A0A028ASS0 A0A028EDA3 A0A029KMF2 A0A066SZI0 A0A069XSD2
(106 more...)
Protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. [EC: 2.7.1.202]
[Protein]-N(pi)-phospho-L-histidine + D-fructose(Side 1) = [protein]-L- histidine + D-fructose 1-phosphate(Side 2).
  • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
  • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
  • The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
  • The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.
  • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
  • Formerly EC 2.7.1.69.
 33 A0A024KZF9 A0A029KMF2 A0A069XSD2 A0A0E1M4A5 A0A0E1SZT7 A0A0F6C780 A0A0F6FAA7 A0A0H3ELU8 A0A0H3PP11 A0A0H3X7G5
(23 more...)
Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208. [EC: 2.7.1.69]
    		7 A0A0A0HAJ6 A0A0D6FXN2 A0A0E2L313 A0A0G3IXJ2 A0A0H2Z129 B7MH43 Q1R8Y3
    Protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. [EC: 2.7.1.191]
    [Protein]-N(pi)-phospho-L-histidine + D-mannose(Side 1) = [protein]-L- histidine + D-mannose 6-phosphate(Side 2).
    • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
    • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
    • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
    • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
    • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
    • Formerly EC 2.7.1.69.
    		 1 I6CIK8