The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Alkaline Phosphatase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 19105: Iduronate 2-sulfatase, putative

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Choline-sulfatase. [EC: 3.1.6.6]
Choline sulfate + H(2)O = choline + sulfate.
    340 A0A017H9G6 A0A021X1S6 A0A024HA49 A0A058YRL9 A0A060I9J9 A0A061CW04 A0A063UG10 A0A066PR40 A0A069BEC7 A0A069PRZ4
    (330 more...)
    Iduronate-2-sulfatase. [EC: 3.1.6.13]
    Hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.
      30 A0A061HUM4 E0W0K2 E6XA82 E6XAT2 F0RBY0 F0RBY5 F0SJC0 F0SJJ9 F0SKE6 F0SMV3
      (20 more...)
      Arylsulfatase. [EC: 3.1.6.1]
      A phenol sulfate + H(2)O = a phenol + sulfate.
      • A group of enzymes with rather similar specificities.
      15 A0A0P0ERW5 A0A120A3Q9 A0A173VHL5 A0A174CNF1 A0A174I9J0 A0A174R6Q6 A0A174S772 A0A1L3GZ56 C6IGG0 I9A011
      (5 more...)
      Pancreatic elastase II. [EC: 3.4.21.71]
      Preferential cleavage: Leu-|-Xaa, Met-|-Xaa and Phe-|-Xaa. Hydrolyzes elastin.
      • Formed by activation of proelastase II from mammalian pancreas by trypsin.
      • Usually, only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species; human pancreatic elastase is of type II.
      • Belongs to peptidase family S1.
      1 C4WMV3
      Cerebroside-sulfatase. [EC: 3.1.6.8]
      A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate.
      • Hydrolyzes galactose-3-sulfate residues in a number of lipids.
      • Also hydrolyzes ascorbate 2-sulfate and many phenol sulfates.
      1 A0A084G4J4
      CATH-Gene3D is a Global Biodata Core Resource Learn more...