The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 63471: L-threonine 3-O-phosphate decarboxylase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Threonine-phosphate decarboxylase. [EC: 4.1.1.81]
L-threonine O-3-phosphate = (R)-1-aminopropan-2-yl phosphate + CO(2).
  • Unable to decarboxylate the D-isomer of threonine O-3-phosphate.
  • The product of this reaction, (R)-1-aminopropan-2-yl phosphate, is the substrate of EC 6.3.1.10, which converts adenosylcobyric acid into adenosylcobinamide phosphate in the anaerobic cobalamin biosynthesis pathway.
321 A0A010SXD3 A0A023CDV3 A0A023NUD5 A0A023WVC5 A0A024HEK0 A0A031GVU5 A0A031MAX1 A0A059L6D2 A0A059UWY3 A0A061JM56
(311 more...)
Histidinol-phosphate transaminase. [EC: 2.6.1.9]
L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
    6 A0A0S4HQ85 A0A0T8KLJ8 A0A0U3AH13 A0A1J5P1D6 A0LCC3 S6JN55
    Adenosylcobinamide-phosphate synthase. [EC: 6.3.1.10]
    (1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate. (2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.
    • This enzyme forms part of the anaerobic cobalamin biosynthesis pathway.
    • One of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (EC 4.1.1.81).
    1 Q88M98
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