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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 63401: LL-diaminopimelate aminotransferase, chloroplastic

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
LL-diaminopimelate aminotransferase. [EC: 2.6.1.83]
LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H(2)O.
  • In vivo, the reaction occurs in the opposite direction to that shown above.
  • This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).
  • Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.
  • 2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.
  • It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate.
 1292 A0A010ZEV4 A0A011UWG5 A0A015Q057 A0A015QF84 A0A015RZ79 A0A015S6G2 A0A015SUI2 A0A015U0J4 A0A015VCN0 A0A015WUR0
(1282 more...)
Aspartate transaminase. [EC: 2.6.1.1]
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
  • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
  • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
 7 A6C2S7 B8BT02 B9RJE0 B9S7T6 B9SD41 B9T7N8 O93744
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