View in Gene3D

CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 63270: Putative nicotianamine aminotransferase B

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Tyrosine transaminase. [EC: 2.6.1.5]
L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
  • L-phenylalanine can act instead of L-tyrosine.
  • The mitochondrial enzyme may be identical with EC 2.6.1.1.
  • The three isoenzymic forms are interconverted by EC 3.4.22.32 and EC 3.4.22.33.
  • The enzyme can also catalyze the final step in the methionine-salvage pathway of Klebsiella pneumoniae.
 45 A0A0A7R9Y3 A0A0B2PCP5 A0A0B2QG98 A0A0B2R6V7 A0A0B2RQB3 A0A0B2RTR1 A0A0P4VRR3 A0A0Q5T4U0 A0A140VKB7 A0A178UPS5
(35 more...)
Nicotianamine aminotransferase. [EC: 2.6.1.80]
Nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine + L-glutamate.
  • This enzyme is produced by grasses.
  • They secrete both the nicotianamine and the transaminated product into the soil around them.
  • Both compounds chelate Fe(2+) and Fe(3+); these chelators, called mugineic acid family phytosiderophores, are taken up by the grass, which is thereby supplied with iron.
 2 Q9ST02 Q9ST03
Aromatic-amino-acid transaminase. [EC: 2.6.1.57]
An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
  • L-methionine can also act as donor, more slowly.
  • Oxaloacetate can act as acceptor.
  • Controlled proteolysis converts the enzyme to EC 2.6.1.1.
 2 M9YSS8 M9YT92
CATH-Gene3D is a Global Biodata Core Resource Learn more...