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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 62814: Probable 4-aminobutyrate aminotransferase, mitocho...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-aminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.19]
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
  • Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
 102 A0A060T0R9 A0A060T0R9 A0A0F8BJV2 A0A0F8BJV2 A0A0F8D0M0 A0A0F8D0M0 A0A0G3VJL6 A0A0G3VJL6 A0A0L1HXL5 A0A0L1HXL5
(92 more...)
(S)-3-amino-2-methylpropionate transaminase. [EC: 2.6.1.22]
(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3- oxopropanoate + L-glutamate.
  • Also acts on beta-alanine and other omega-amino acids having carbon chains between 2 and 5.
  • The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.
 18 K0KXA4 K0KXA4 M5FJQ7 M5FJQ7 P50554 P50554 P61922 P61922 P80147 P80147
(8 more...)
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    		 2 A0A0E9NJU6 A0A0E9NJU6
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