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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 61844: L-seryl-tRNA(Sec) selenium transferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-seryl-tRNA(Sec) selenium transferase. [EC: 2.9.1.1]
L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate.
  • Recognizes specifically tRNA(Sec)-species.
  • Binding of tRNA(Sec) also occurs in the absence of the seryl group.
  • 2-aminoacryloyl-tRNA, bound to the enzyme as an imine with the pyridoxal phosphate, is an intermediate in the reaction.
  • Since the selenium atom replaces oxygen in serine, the product may also be referred to as L-selenoseryl-tRNA(Sel).
  • The abbreviation Sel has also been used for selenocysteine but Sec is preferred.
 263 A0A024BYP6 A0A024CA55 A0A060PTH2 A0A083YEJ0 A0A086RRP9 A0A0B2DW79 A0A0B2E5A1 A0A0B2E8T1 A0A0B2EBK0 A0A0B2EH54
(253 more...)
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