The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42754: 8-amino-7-oxononanoate synthase/2-amino-3-ketobuty...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
8-amino-7-oxononanoate synthase. [EC: 2.3.1.47]
Pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO(2) + holo-[acyl-carrier protein].
  • The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.
  • Pimeloyl-CoA can be used with lower efficiency.
20 A0A0B0SEI9 A0A0D6XA39 A0A0M9ACE5 A0A0N0ZRB2 A0A120HT38 A0A1J0LU73 A0A1J1EUD3 B7A9M5 E4U9V0 E8PPM5
(10 more...)
Glycine C-acetyltransferase. [EC: 2.3.1.29]
Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate.
  • Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.
  • This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex.
1 Q5SHZ8
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