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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1323: Glutamate decarboxylase eukaryotic type

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate decarboxylase. [EC: 4.1.1.15]
L-glutamate = 4-aminobutanoate + CO(2).
  • The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
 11 A0A0E4CEI8 A0A0H3AK76 A0A0H3Q133 A0A0H6HAH5 A0A0K9UT59 A0A0X1KVV4 C2HX38 C3LLJ6 D0HFW6 D0IFQ4
(1 more...)
Diaminobutyrate decarboxylase. [EC: 4.1.1.86]
L-2,4-diaminobutanoate = propane-1,3-diamine + CO(2).
  • N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates.
  • In Acinetobacter baumannii it is cotranscribed with the neighboring dat gene that encodes EC 2.6.1.76, which can supply the substrate for the decarboxylase.
 9 A0A0H3AK76 A0A0H3Q133 A0A0H6HAH5 A0A0H6HQP3 A0A0H6KPP7 A0A0K9UT59 A0A0X1KVV4 C3LLJ6 Q9KSV7
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