View in Gene3D

CATH Superfamily 3.40.630.30

Gcn5-related N-acetyltransferase (GNAT)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 70594: L-2,4-diaminobutyric acid acetyltransferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Diaminobutyrate acetyltransferase. [EC: 2.3.1.178]
Acetyl-CoA + L-2,4-diaminobutanoate = CoA + N(4)-acetyl-L-2,4- diaminobutanoate.
  • Ornithine, lysine, aspartate, and alpha-, beta- and gamma- aminobutanoate cannot act as substrates.
  • However, acetyl-CoA can be replaced by propanoyl-CoA, although the reaction proceeds more slowly.
  • Forms part of the ectoine biosynthesis pathway, the other enzymes involved being EC 2.6.1.76 and EC 4.2.1.108.
 534 A0A031JJZ5 A0A031JJZ5 A0A058YYT6 A0A058YYT6 A0A063UQF7 A0A063UQF7 A0A066PZN4 A0A066PZN4 A0A072FLX9 A0A072FLX9
(524 more...)
Acetate--CoA ligase (ADP-forming). [EC: 6.2.1.13]
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.
  • Also acts on propanoate and, very slowly, on butanoate.
 124 A0A027TYL6 A0A027TYL6 A0A028ASA8 A0A028ASA8 A0A028E2Y3 A0A028E2Y3 A0A029HNU7 A0A029HNU7 A0A029IMP9 A0A029IMP9
(114 more...)
Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.
  • Differs from EC 2.6.1.46, which has pyruvate as the amino-group acceptor.
  • This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
 6 A0A143QRG5 A0A143QRG5 A0A165MJW0 A0A165MJW0 X5UK13 X5UK13
Succinate--CoA ligase (ADP-forming). [EC: 6.2.1.5]
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.
    		 4 D4E2H4 D4E2H4 F5S0R5 F5S0R5
    CATH-Gene3D is a Global Biodata Core Resource Learn more...