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CATH Superfamily 3.40.630.30

Gcn5-related N-acetyltransferase (GNAT)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 70336: Putative acetyltransferase, GNAT family

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aminoglycoside 6'-N-acetyltransferase. [EC: 2.3.1.82]
Acetyl-CoA + kanamycin-B = CoA + N(6')-acetylkanamycin-B.
  • The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C(1a), gentamicin C(2), sisomicin and tobramycin are substrates.
  • The antibiotic paromomycin is not a substrate.
  • The 6-amino group of the purpurosamine ring is acetylated.
  • Formerly EC 2.3.1.55.
 868 A0A009K866 A0A009K866 A0A009KLL0 A0A009KLL0 A0A022IAZ9 A0A022IAZ9 A0A024ITP4 A0A024ITP4 A0A031J7A6 A0A031J7A6
(858 more...)