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CATH Superfamily 3.40.630.30

Gcn5-related N-acetyltransferase (GNAT)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39566: Aminoglycoside N(6')-acetyltransferase type 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aminoglycoside 6'-N-acetyltransferase. [EC: 2.3.1.82]
Acetyl-CoA + kanamycin-B = CoA + N(6')-acetylkanamycin-B.
  • The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C(1a), gentamicin C(2), sisomicin and tobramycin are substrates.
  • The antibiotic paromomycin is not a substrate.
  • The 6-amino group of the purpurosamine ring is acetylated.
  • Formerly EC 2.3.1.55.
 6 A0A0U5HUT0 A0A0X3R5M4 B2FQI3 E5LCR5 J7SZI0 Q9RBW7