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CATH Superfamily 3.40.630.10

Zn peptidases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Zn peptidases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6073: Glutamate carboxypeptidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate carboxypeptidase. [EC: 3.4.17.11]
Release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups.
  • Produced by pseudomonads, Flavobacterium sp. and Acinetobacter sp.
  • Its ability to hydrolyze pteroyl-L-glutamate (folic acid) has led to its use as a folate-depleting, antitumor agent.
  • Belongs to peptidase family M20A.
 11 A0A0A8RHA6 A0A0D6HBF8 A0A0F6UC04 A0A0H2ZCQ0 A0A0P1DAX8 A0A157W7W4 A0A1F0J6X4 A0A1G5KLP4 A0A1J0IU17 A0A1L4GZK5
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