The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1856: Aldehyde dehydrogenase A, NAD-linked

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Lactaldehyde dehydrogenase. [EC: 1.2.1.22]
(S)-lactaldehyde + NAD(+) + H(2)O = (S)-lactate + NADH.
    211 A0A023YXB7 A0A024KW87 A0A024L3U1 A0A025C5K3 A0A026UHB0 A0A029I4X4 A0A029IV98 A0A029PQ63 A0A060V5Q4 A0A064E541
    (201 more...)
    Glycolaldehyde dehydrogenase. [EC: 1.2.1.21]
    Glycolaldehyde + NAD(+) + H(2)O = glycolate + NADH.
      175 A0A023YXB7 A0A024KW87 A0A024L3U1 A0A025C5K3 A0A026UHB0 A0A029I4X4 A0A029IV98 A0A029KWL0 A0A029LMR4 A0A029PQ63
      (165 more...)
      Succinate-semialdehyde dehydrogenase (NAD(P)(+)). [EC: 1.2.1.16]
      Succinate semialdehyde + NAD(P)(+) + H(2)O = succinate + NAD(P)H.
        1 F5RYC2
        CATH-Gene3D is a Global Biodata Core Resource Learn more...