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CATH Superfamily 3.40.600.10

DNA mismatch repair MutH/Restriction endonuclease, type II

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
DNA mismatch repair MutH/Restriction endonuclease, type II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Type-2 restriction enzyme HindII

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Type II site-specific deoxyribonuclease. [EC: 3.1.21.4]
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
  • Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 2 P17743 P44413