The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
CRAL-TRIO lipid binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2393: Neurofibromin 1, isoform F

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
5 A0A0B4KHX4 (/IDA) A0A0B4KI28 (/IDA) Q59DT9 (/IDA) Q8IMS2 (/IDA) Q9VBJ2 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
5 A0A0B4KHX4 (/IGI) A0A0B4KI28 (/IGI) Q59DT9 (/IGI) Q8IMS2 (/IGI) Q9VBJ2 (/IGI)
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Perineurial glial growth GO:0042066
Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.
5 A0A0B4KHX4 (/IGI) A0A0B4KI28 (/IGI) Q59DT9 (/IGI) Q8IMS2 (/IGI) Q9VBJ2 (/IGI)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Positive regulation of adenylate cyclase activity GO:0045762
Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)
Regulation of Ras protein signal transduction GO:0046578
Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
5 A0A0B4KHX4 (/IMP) A0A0B4KI28 (/IMP) Q59DT9 (/IMP) Q8IMS2 (/IMP) Q9VBJ2 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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