View in Gene3D

CATH Superfamily 3.40.50.980

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 69894: 2,3-dihydroxybenzoate-AMP ligase [enterobactin] si...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(2,3-dihydroxybenzoyl)adenylate synthase. [EC: 2.7.7.58]
ATP + 2,3-dihydroxybenzoate = diphosphate + (2,3- dihydroxybenzoyl)adenylate.
    		 764 A0A011U6G7 A0A011U6G7 A0A023P673 A0A023P673 A0A023Y396 A0A023Y396 A0A026RM01 A0A026RM01 A0A029KRF6 A0A029KRF6
    (754 more...)
    Isochorismate synthase. [EC: 5.4.4.2]
    Chorismate = isochorismate.
    • The reaction is reversible.
    • Formerly EC 5.4.99.6.
    		 8 A0A088X566 A0A088X566 A0A0D5L4D2 A0A0D5L4D2 A0A1B4ACX7 A0A1B4ACX7 H0U6D6 H0U6D6
    Long-chain-fatty-acid--CoA ligase. [EC: 6.2.1.3]
    ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA.
    • Acts on a wide range of long-chain saturated and unsaturated fatty acids, but the enzymes from different tissues show some variation in specificity.
    • The liver enzyme acts on acids from C(6) to C(20); that from brain shows high activity up to C(24).
    		 4 A0A1J0UJK0 A0A1J0UJK0 F2R7A5 F2R7A5
    Anthranilate synthase. [EC: 4.1.3.27]
    Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
    • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20, and EC 5.3.1.24).
    • The native enzyme in the complex with uses either glutamine or (less efficiently) NH(3).
    • The enzyme separated from the complex uses NH(3) only.
    		 2 D8P4S5 D8P4S5