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CATH Superfamily 3.40.50.970

Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36603: Acetolactate synthase large subunit

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetolactate synthase. [EC: 2.2.1.6]
2 pyruvate = 2-acetolactate + CO(2).
  • The reaction shown is in the pathway of biosynthesis of valine.
  • The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
  • Formerly EC 4.1.3.18.
 336 A0A034TZA0 A0A034TZA0 A0A066UTG0 A0A066UTG0 A0A067BL15 A0A067BL15 A0A084TGG7 A0A084TGG7 A0A085PDI1 A0A085PDI1
(326 more...)
Cyclohexane-1,2-dione hydrolase. [EC: 3.7.1.11]
Cyclohexane-1,2-dione + H(2)O = 6-oxohexanoate.
  • Highly specific; does not act on cyclohexanone or cyclohexane-1,3- dione as substrate.
 2 P0CH62 P0CH62
Benzoin aldolase. [EC: 4.1.2.38]
Benzoin = 2 benzaldehyde.
    		 2 P51853 P51853