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CATH Superfamily 3.40.50.970

Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36507: Probable 2-hydroxyacyl-CoA lyase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Oxalyl-CoA decarboxylase. [EC: 4.1.1.8]
Oxalyl-CoA = formyl-CoA + CO(2).
    		 1098 A0A016XHL7 A0A016XHL7 A0A022GFT8 A0A022GFT8 A0A023Z0Q6 A0A023Z0Q6 A0A024KYA0 A0A024KYA0 A0A025CWH4 A0A025CWH4
    (1088 more...)
    Benzoin aldolase. [EC: 4.1.2.38]
    Benzoin = 2 benzaldehyde.
      		 4 A0A174BGS6 A0A174BGS6 D2Q6H6 D2Q6H6
      Acetolactate synthase. [EC: 2.2.1.6]
      2 pyruvate = 2-acetolactate + CO(2).
      • The reaction shown is in the pathway of biosynthesis of valine.
      • The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
      • Formerly EC 4.1.3.18.
      		 2 A0A0T9TJ03 A0A0T9TJ03