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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 48428: Putative short-chain type dehydrogenase/reductase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
7-alpha-hydroxysteroid dehydrogenase. [EC: 1.1.1.159]
3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD(+) = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH.
  • Catalyzes the oxidation of the 7-alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms.
  • The Bacteroides fragilis and Clostridium enzymes can also utilize NADP(+).
 42 A0A049DWM2 A0A0E2WX99 A0A0E7WN20 A0A0H3A3N4 A0A0H3LDM5 A0A0H3M4R4 A0A0H3P563 A0A0T7LAF9 A0A0T9BFN7 A0A0T9BLD0
(32 more...)
D-iditol 2-dehydrogenase. [EC: 1.1.1.15]
D-iditol + NAD(+) = D-sorbose + NADH.
  • Also converts xylitol into L-xylulose and L-glucitol into L-fructose.
 1 A0A0G4DUX5