The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42848: Short chain dehydrogenase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2,4-dienoyl-CoA reductase (NADPH). [EC: 1.3.1.34]
Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5- tetradehydroacyl-CoA + NADPH.
  • Best substrates for reduction contain a 2,4-diene structure with chain length C(8) or C(10).
24 A0A0A0TQU6 A0A0G3VA76 A0A0K6KKN3 A0A0K6KKQ1 A0A0K6LLK3 A0A0K6MC31 A0A0M0L1A7 A0A0T8PXJ4 A0A0U0C7D1 A0A125UGZ6
(14 more...)
Glucose 1-dehydrogenase (NAD(P)(+)). [EC: 1.1.1.47]
D-glucose + NAD(P)(+) = D-glucono-1,5-lactone + NAD(P)H.
  • This enzyme has similar activity with either NAD(+) or NADP(+).
  • Cf. EC 1.1.1.118 and EC 1.1.1.119.
12 A0A0G3VA76 A0A0T8PXJ4 A0A0U0C7D1 A0A125UGZ6 A0A162Q768 A0A1D8FJQ3 A0A1D9PIQ8 A7Z422 D4FVY6 G4EWZ9
(2 more...)