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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39672: 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydro...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-alpha-hydroxysteroid 3-dehydrogenase (Si-specific). [EC: 1.1.1.50]
A 3-alpha-hydroxysteroid + NAD(P)(+) = a 3-oxosteroid + NAD(P)H.
  • The enzyme acts on androsterone and other 3-alpha-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin.
  • Si-specific with respect to NAD(+) or NADP(+) (cf. EC 1.1.1.213).
 18 A0A0N0W436 A0A0N0WP76 A0A0N8RTF5 A0A0P9J339 A0A0P9MCY8 A0A0P9N1T9 A0A0P9NKM0 A0A0P9QZW1 A0A0P9UMS1 A0A0P9W6H0
(8 more...)