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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291914: Cinnamyl alcohol dehydrogenase 2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.2]
An alcohol + NADP(+) = an aldehyde + NADPH.
  • Some members of this group oxidize only primary alcohols; others act also on secondary alcohols.
  • May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55.
  • Re-specific with respect to NADPH.
 164 A0A024L8S1 A0A028ARG3 A0A028E6X4 A0A029JZ03 A0A029L6E5 A0A062Y0S9 A0A066P2L5 A0A070CEI6 A0A070DH51 A0A070UQY6
(154 more...)
Alcohol dehydrogenase. [EC: 1.1.1.1]
(1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
  • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
  • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
 71 A0A023Z7G7 A0A064DC96 A0A084ZMM2 A0A085GP53 A0A085HDY1 A0A085IEP3 A0A085JPW5 A0A094VUC2 A0A0A0F649 A0A0A1RCF6
(61 more...)
Cinnamyl-alcohol dehydrogenase. [EC: 1.1.1.195]
Cinnamyl alcohol + NADP(+) = cinnamaldehyde + NADPH.
  • Acts on coniferyl alcohol, sinapyl alcohol, 4-coumaryl alcohol and cinnamyl alcohol (cf. EC 1.1.1.194).
 4 D2T9K0 D4I3P8 E5BAB6 V5ZCJ4