The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 291911: Pteridine reductase 1
There are 6 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Pteridine reductase.
[EC: 1.5.1.33]
5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 NADPH.
|
12 |
A0A088SA10
A0A088SA10
A4HCP1
A4HCP1
A4I067
A4I067
E9BG51
E9BG51
P42556
P42556 (2 more...) |
Thymidylate synthase.
[EC: 2.1.1.45]
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
|
8 | A0A088SA10 A0A088SA10 A4HCP1 A4HCP1 A4I067 A4I067 E9BG51 E9BG51 |
Dihydrofolate reductase.
[EC: 1.5.1.3]
5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH.
|
6 | A4HCP1 A4HCP1 A4I067 A4I067 E9BG51 E9BG51 |
3-oxoacyl-[acyl-carrier-protein] reductase.
[EC: 1.1.1.100]
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
|
4 | A0A0F4Z0E1 A0A0F4Z0E1 A2QQB6 A2QQB6 |
6,7-dihydropteridine reductase.
[EC: 1.5.1.34]
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine + NAD(P)H.
|
2 | A0A088SA10 A0A088SA10 |
L-xylulose reductase.
[EC: 1.1.1.10]
Xylitol + NADP(+) = L-xylulose + NADPH.
|
2 | G3YG17 G3YG17 |